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Buspirone Hydrochloride (HCL) is an anxiety medication prescribed for management of anxiety disorders or short-term relief of anxiety symptoms. Buspirone is in tablet form and comes in 5mg, 10mg, 15mg and 30mg strengths.

COMPLEMENTARY AND ALTERNATIVE MEDICINE

Individuals with anxiety related emotional disturbances often find relief for some of their symptoms when taking natural alternatives like St. Johns Wort, Kava Kava, Valerian Root, Passion Flower and 5-HTP. Clinical studies suggest that natural alternatives like the ones mentioned above may be similarily as effective in relieving some forms of anxiety as prescription medications. Less than 1.5% of users of CAM therapies report adverse side effects. Visit the homepages for the most popular alternative medicines by choosing a product below.

CAM therapies are not a substitute for Prescription Medications or professional medical advice.*

WHERE TO BUY BUSPAR

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In vitro studies have shown that Buspar has a high affinity for serotonin receptors (receptors in the brain that mediate arousal). Buspar has no significant affinity for benzodiazepine receptors in the brain.

HOW EFFECTIVE IS BUSPAR?

The excellent efficacy of Buspar has been demonstrated in controlled clinical trials of outpatients with a diagnosis of Generalized Anxiety Disorder (GAD).

The patients evaluated in these studies had experienced symptoms for periods of 1 month to over 1 year prior to the study, with an average symptom duration of 6 months. Generalized, persistent anxiety (of at least one month continual duration), manifested by symptoms from three of the four following categories :
Motor tension: Shakiness, jitteriness, jumpiness, trembling, tension, muscle aches, fatigability, inability to relax, eyelid twitch, furrowed brow, strained face, fidgeting, restlessness, easy startle.

The effectiveness of Buspar in long-term use, that is, for more than 3 to 4 weeks, has not been demonstrated in controlled trials. There is no body of evidence available that systematically addresses the appropriate duration of treatment for GAD. However, in a study of long-term use, 264 patients were treated with Buspar for 1 year without ill effect. Therefore, the physician who elects to use Buspar for extended periods should periodically reassess the usefulness of the drug for the individual patient.

DOSAGE AND ADMINISTRATION :

The recommended initial dose is 15 mg daily (5 mg 3 times a day). To achieve an optimal therapeutic response, at intervals of 2 to 3 days the dosage may be increased 5 mg per day, as needed. The maximum daily dosage should not exceed 60 mg per day. In clinical trials allowing dose titration, divided doses of 20 to 30 mg per day were commonly employed.

ADVERSE REACTIONS & SIDE EFFECTS

The more commonly observed untoward events associated with the use of Buspar not seen at an equivalent incidence among placebo-treated patients include dizziness, nausea, headache, nervousness, lightheadedness, and excitement.

Other common adverse events included: central nervous system disturbances (3.4%), primarily dizziness, insomnia, nervousness, drowsiness, and lightheaded feeling; gastrointestinal disturbances (1.2%), primarily nausea; and miscellaneous disturbances (1.1%), primarily headache and fatigue.

Interference with cognitive and motor performance: Studies indicate that Buspar is less sedating than other anti-anxiety medications and that it does not produce significant functional impairment. However, its CNS effects in any individual patient may not be predictable.

Therefore, patients should be cautioned about operating an automobile or using complex machinery until they are reasonably certain that Buspar treatment does not affect them adversely.
While formal studies of the interaction of Buspar with alcohol indicate that Buspar does not increase alcohol-induced impairment in motor and mental performance, it is prudent to avoid concomitant use of alcohol and Buspar.

DRUG ABUSE AND DEPENDENCE :

Although there is no direct evidence that Buspar causes physical dependence or drug-seeking behavior, it is difficult to predict from experiments the extent to which a CNS-active drug will be misused.

BE SURE TO INCLUDE THE FOLLOWING INFORMATION IN YOUR PHYSICAL EXAMINATION/MEDICAL QUESTIONNAIRE :

Include any medications, prescription or non-prescription, alcohol, or drugs that you are now taking or plan to take during your treatment with BUSPAR.

Note if you are pregnant, or if you are planning to become pregnant while you are taking BUSPAR.